Independent Quality Testing & APICOA Verified\u2122 Certification
Every API ingredient undergoes rigorous third-party analytical testing by APICOA — including LC-MS/MS identity confirmation, purity validation, and contaminant screening — before receiving the APICOA Verified\u2122 certification.
How APICOA Tests Every Batch
Four categories of analytical testing ensure every API ingredient meets pharmaceutical-grade identity, purity, safety, and quality standards.
LC-MS/MS Identity Testing
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) provides definitive molecular identification of each API ingredient. This gold-standard technique confirms the compound matches its labeled identity with >99.9% confidence.
Purity & Potency Validation
High-Performance Liquid Chromatography (HPLC) with UV/Vis detection quantifies the active ingredient concentration and identifies any impurities. Each batch must meet predefined acceptance criteria before certification.
Contaminant Screening
Comprehensive contaminant screening covers heavy metals (ICP-MS), residual solvents (GC-MS), microbial limits, and endotoxin testing. All results are compared against USP, EP, and ICH Q3D limits.
Physical Characterization
Physical properties including appearance, color, particle size, moisture content, and melting point are documented for each batch. These parameters ensure the API meets pharmaceutical-grade specifications.
From Sample to APICOA Verified\u2122
Every batch follows a strict 6-step testing and certification process before receiving the APICOA Verified\u2122 mark.
Sample Receipt & Logging
Samples arrive from Origin API's distribution hub with full chain-of-custody documentation. Each sample is logged, assigned a unique lab ID, and enters the testing queue.
Identity Confirmation
LC-MS/MS analysis confirms the molecular identity of the API ingredient matches its label claim. Results are compared against certified reference standards.
Purity & Potency Analysis
HPLC quantification determines the assay value (potency) and identifies any related substances or impurities above reporting thresholds.
Safety Screening
Heavy metals, residual solvents, microbial limits, and endotoxin levels are tested against pharmacopeial limits (USP, EP, ICH Q3D).
COA Generation
All results are compiled into a Certificate of Analysis with batch-specific data, test methods, acceptance criteria, and pass/fail determinations.
APICOA Verified™ Certification
Batches that pass all testing criteria receive the APICOA Verified™ mark. Digital verification is enabled, and the batch is approved for distribution.
The APICOA Verified\u2122 Advantage
Independent, third-party verification that gives you and your customers confidence in every API ingredient.
Third-Party Independence
APICOA operates independently from Origin API, ensuring unbiased test results and true third-party verification of every batch.
Pharmaceutical-Grade Standards
Testing follows USP, EP, and ICH guidelines — the same standards used by FDA-regulated pharmaceutical manufacturers.
Digital Verification
Every APICOA Verified™ COA includes a digital verification code that can be validated online to confirm authenticity.
State-of-the-Art Equipment
LC-MS/MS, HPLC, ICP-MS, GC-MS, and other advanced analytical instruments ensure the highest analytical accuracy.
Trust Verified, Not Claimed
Every API ingredient we distribute comes with independent APICOA Verified\u2122 certification. See the difference third-party testing makes.