Certificate of Analysis

Understanding Your Certificate of Analysis

Every API ingredient distributed through Origin API comes with a comprehensive APICOA Verified\u2122 Certificate of Analysis — your proof of identity, purity, potency, and safety backed by independent third-party testing.

COA Anatomy

What's Inside an APICOA Verified\u2122 COA

Each Certificate of Analysis contains six key sections covering identity, purity, safety, and certification status of the tested batch.

Product Identification

Product name, batch/lot number, manufacturer, date of manufacture, expiry date, and quantity. This section uniquely identifies the specific batch being certified.

Product Name & Grade
Batch/Lot Number
Manufacturer & Country of Origin
Date of Manufacture & Expiry

Identity Testing Results

LC-MS/MS and/or FTIR identity confirmation results showing the compound matches its label claim. Includes molecular weight, fragmentation patterns, and reference standard comparison.

LC-MS/MS Identity Result
Molecular Weight Confirmation
Reference Standard Comparison
Identity Test: PASS/FAIL

Purity & Potency (Assay)

HPLC-UV/Vis assay results showing the active ingredient concentration (potency) and related substance/impurity levels. Each result is compared against predefined acceptance criteria.

Assay Value (%w/w)
Related Substances (% each)
Total Impurities (%)
Acceptance Criteria & Result

Contaminant & Safety Testing

Heavy metals (ICP-MS), residual solvents (GC-MS), microbial limits, and endotoxin testing results. All compared against USP/ICH Q3D limits.

Heavy Metals (Pb, Cd, As, Hg)
Residual Solvents
Microbial Limits (TAMC/TYMC)
Bacterial Endotoxins

Physical Characteristics

Appearance, color, odor, moisture content (Karl Fischer), particle size, pH, and melting/boiling point as applicable to the specific compound.

Appearance & Color
Moisture Content (KF)
Particle Size Distribution
Melting Point / pH

Certification & Verification

APICOA Verified™ certification mark, digital verification code, QA release signature, date of analysis, and overall batch disposition (approved/rejected).

APICOA Verified™ Mark
Digital Verification Code
QA Release Signature & Date
Batch Disposition: APPROVED
Digital Verification

Verify Any COA Digitally

Every APICOA Verified\u2122 COA includes a unique digital verification code. This code can be used to confirm the authenticity of the document, verify test results haven't been altered, and download a digitally-signed copy.

1

Locate the Verification Code

Find the unique alphanumeric verification code printed on the COA, typically in the top-right corner or certification section.

2

Visit the Verification Portal

Go to the APICOA digital verification portal and enter the verification code in the search field.

3

Confirm Authenticity

The portal displays the original COA data including test results, batch information, and certification date. Compare with your physical COA.

4

Download Verified Copy

Download a digitally-signed PDF copy of the COA directly from the verification portal for your records.

APICOA Verified\u2122

Sample Verification Result

ProductBPC-157 (Pentadecapeptide)
BatchOA-2026-03-1547
Purity99.2% (HPLC)
IdentityCONFIRMED (LC-MS/MS)
Heavy MetalsPASS (<10 ppm)
MicrobialPASS (USP <61>)
StatusAPPROVED FOR DISTRIBUTION
Verification Code: APV-2026-1547-XR9
Common Questions

COA Frequently Asked Questions

Everything you need to know about Certificates of Analysis and the APICOA Verified\u2122 certification.

What makes an APICOA COA different from a manufacturer's COA?

A manufacturer's COA contains self-reported test results. An APICOA COA is generated from independent third-party testing using calibrated instruments and certified reference standards — providing unbiased verification that the product meets specifications.

How quickly are COAs generated after testing?

Standard turnaround is under 48 hours from sample receipt. Rush testing is available for time-sensitive orders with turnaround as fast as 24 hours.

Can I verify a COA is authentic?

Yes. Every APICOA Verified™ COA includes a unique digital verification code that can be validated through the APICOA verification portal, confirming the document hasn't been altered or forged.

What standards are tests performed against?

Testing follows USP (United States Pharmacopeia), EP (European Pharmacopoeia), and ICH (International Council for Harmonisation) guidelines, including ICH Q3D for elemental impurities.

Do COAs accompany every shipment?

Yes. Every batch shipped through Origin API includes a complete APICOA Verified™ COA in both physical and digital formats as part of the documentation package.

Every Batch. Every COA. Verified.

Stop trusting manufacturer self-reported COAs. Get independent, third-party verified Certificates of Analysis with every order.